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Autologous Mixed Lymphocyte Reaction in Man
Author(s) -
Hwang KungChang,
Fikrig Senih M.,
Friendman Howard M.,
Gupta Sudhir
Publication year - 1983
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1983.tb01594.x
Subject(s) - mixed lymphocyte reaction , atopic dermatitis , asthma , immunology , lymphocyte , medicine , allergic dermatitis , hypersensitivity reaction , allergic reaction , allergy , immune system , t cell
The proliferative response of T lymphocyte cultured with autologous non‐T lymphocyte is known as the autologous mixed lymphocyte reaction (AMLR). In AMLR. Both helper and suppressor functions are generated. In this investigation we have examined I cell proliferative responses in AMLR in 12 patients with bronchia asthma 10 patients with allergic rhinitis, and 10 patients with atopic dermatitis and compared that with simultaneously with bronchial asthma is significantly higher than that of health normals. However, AMRL response in patients with allergic rhinitis or atopic dermatitis is comparable to controls. Mechanisms for increased AMLR in patients with bronchial asthma are discussed.