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Comparison of the Protective Effect of Ketotifen and Disodium Cromoglycate on Exercise‐Induced Asthma in Asthmatic Boys
Author(s) -
Lilja Gunnar,
GraffLonnevig Viggo,
Bevegåd Sture
Publication year - 1983
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1983.tb00853.x
Subject(s) - ketotifen , disodium cromoglycate , medicine , asthma , exercise induced asthma , anesthesia
Fourteen hoys with a mean age of 12.2 years were studied with respect to the protective effect of ketotifen on exercise‐induced asthma (EIA) in comparison with disodium cromoglycate (DSCG). All had a positive history of EIA and a post‐exercise fall in FEV 1 of more than 20%. A double blind cross‐over technique was used with a 1 week wash‐out period between the two treatment alternatives. Both drugs gave some, but not significant protection for EIA and no differences between the two active substances tested were found. Great individual differences in the response to the two drugs were noted.