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Human Serum IgE against Two Major Allergens from Cow Hair and Dander: Determination of Affinity and Quantity of Antigen‐Specific IgE
Author(s) -
Prahl P.,
Nexø E.
Publication year - 1982
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1982.tb04116.x
Subject(s) - immunoglobulin e , dander , radioimmunoassay , immunology , antigen , antibody , allergen , allergy , medicine , chemistry , biochemistry
The quantity and quality of antigen‐specific IgE against purified major allergens from cow hair and dander was measured by a double‐antibody radioimmunoassay. In serum from patients with allergic asthma to cow the affinity constant varied from 1 to 150 × 10 9 1/mol and the number of antibody combining sites from 0.01 to 0.4 × 10 −9 mol/1 serum for each antigen.