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THE EFFECT OF ORAL DOXANTRAZOLE ON ALLERGEN‐INDUCED BRONCHOSPASM
Author(s) -
PAUWELS R.,
LAMONT H.,
STRAETEN M.
Publication year - 1976
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1976.tb01684.x
Subject(s) - medicine , university hospital , general hospital , bronchospasm , general surgery , library science , family medicine , asthma , computer science
The protective effect of 200 mg doxantrazole given orally on allergen-induced bronchoconstriction has been compared with 20 mg inhaled disodium cromoglycate (DSCG) in 15 patients with bronchial asthma and immediate-type hypersensitivity. Only four out of the 15 patients showed a significant inhibition of their bronchoconstriction after the oral intake of doxantrazole. Nine patients were significantly protected by 20 mg DSCG. All patients responding to doxantrazole also responded well to DSCG.