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ICI 74,917: A NEW ANTI‐ALLERGIC DRUG ADMINISTERED BY PRESSURISED AEROSOL
Author(s) -
MYGIND NIELS,
THOMSEN JENS
Publication year - 1975
Publication title -
allergy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1975.tb00206.x
Subject(s) - library science , medicine , psychology , family medicine , computer science
Ten patients with allergic rhinitis were challenged intranasally with allergen before, and half an hour, 2 hours and 4 hours after intranasal administration of placebo, disodium cromoglycate powder and an aerosol containing ICI 74,917, a new compound with anti-allergic action. ICI 74,917 had a maximum protective effect after half an hour, but was significantly better than placebo 2 hours after nasal use. The effect was significantly better than that of disodium cromoglycate powder. The results will encourage studies of ICI 74,917 in the treatment of allergic rhinitis.