Open AccessComparison of survival of exfoliative glaucoma patients and primary open‐angle glaucoma patients: impact of acetazolamide use
Author(s) -
Ritland J. S.,
Egge K.,
Lydersen S.,
Juul R.,
Semb S. O.
Publication year - 2004
Publication title -
acta ophthalmologica scandinavica
Language(s) - English
Resource type - Journals
eISSN - 1600-0420
pISSN - 1395-3907
DOI - 10.1111/j.1395-3907.2004.00296.x
Subject(s) - medicine , acetazolamide , glaucoma , open angle glaucoma , survival analysis , ophthalmology , proportional hazards model
. Purpose: To compare the survival rates of patients with exfoliative glaucoma (XFG) and those with primary open‐angle glaucoma (POAG), and to establish whether the use of acetazolamide has any influence on survival.Methods: The survival data, including date and cause of death, for 1147 patients with XFG or POAG who were ultimately hospitalized at the Eye Department, National Hospital, Oslo, between 1961 and 1970, were analysed retrospectively. The Cox proportional hazard model was used in the survival analyses.Results: No statistically significant differences in survival were found between patients with XFG and those with POAG (p = 0.85). As expected, female gender and younger age at diagnosis were associated with longer survival periods. Surprisingly, we found that patients with more recent birth dates had relatively lower survival rates than patients with earlier birth dates; when this was included in the analyses, the use of acetazolamide was found to be associated with reduced survival ( n = 492, p = 0.02).