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REVIEW: Movement disorders and alcohol misuse
Author(s) -
Hess Christopher W.,
SaundersPullman Rachel
Publication year - 2006
Publication title -
addiction biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.445
H-Index - 78
eISSN - 1369-1600
pISSN - 1355-6215
DOI - 10.1111/j.1369-1600.2006.00017.x
Subject(s) - movement disorders , parkinsonism , dystonia , tics , myoclonus , psychiatry , chorea , psychology , alcohol abuse , comorbidity , alcohol use disorder , medicine , alcohol , neuroscience , disease , biochemistry , chemistry
Many movement disorders, including tics, chorea, tremor, myoclonus and parkinsonism, may result from substance abuse. However, alcohol in particular is associated in a more complex manner with two specific movement disorders, essential tremor (ET) and myoclonus–dystonia (M‐D). In this review we discuss the comorbidity of alcohol abuse in both ET and M‐D, the ameliorative effects of alcohol in both diseases, and review the data evaluating alcohol abuse secondary to self‐medication. We also discuss shared pathophysiologic mechanisms in the understanding of both of these disorders, as the elucidation of the mechanisms by which alcohol exerts its effects may lead to novel therapeutic approaches.