Open AccessMetoclopramide for migraine‐associated hiccup
Author(s) -
Gupta V. K.
Publication year - 2006
Publication title -
international journal of clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 98
eISSN - 1742-1241
pISSN - 1368-5031
DOI - 10.1111/j.1368-5031.2006.00844.x
Subject(s) - medicine , metoclopramide , migraine , nausea , anesthesia , dopaminergic , vomiting , dopamine
Summary Persistent hiccup can be a distressing disorder. I present a case of migraine‐attack‐associated sustained hiccup. Metoclopramide can swiftly control both hiccup and migraine headache. Vasopressin release probably underlies migraine‐aborting action of metoclopramide while restoration of oesophageal smooth muscle function involves competitive dopaminergic antagonism and a prominent cholinergic agonist activity. Episodic prolonged hiccup associated with nausea is an unusual presenting feature of migraine.