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Hematological study of patients with aphthous stomatitis
Author(s) -
LopezJornet Pia,
CamachoAlonso Fabio,
Martos Nieves
Publication year - 2014
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2012.05751.x
Subject(s) - medicine , recurrent aphthous stomatitis , hematinic , vitamin b12 , gastroenterology , stomatitis , folic acid , ferritin , pediatrics , immunology
Objectives A study was made of the association between recurrent aphthosis ( RAS ) and iron, ferritin, vitamin B 12, and folic acid deficiency. Methods A total of 186 adults were consecutively recruited: 92 subjects with RAS (28 males and 64 females, with a mean age of 41 years) and 94 controls (20 men and 74 women, with a mean age of 44 years), and subjected to clinical and hematological evaluation. Results The overall frequency of hematinic deficiencies was 14.14% in the RAS group versus 6.39% in the control group ( P = 0.086). Patient age and a family history of aphthosis were associated to the presence of RAS . Conclusion There is still no conclusive evidence relevant to the etiopathogenesis of RAS . Routine hematological screening and tests for serum iron, folic acid, and vitamin B 12 deficiencies should be assessed in all patients with RAS .