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Intermediate/borderline disseminated cutaneous leishmaniasis
Author(s) -
Paniz Mondolfi Alberto E.,
Duffey Gabrielle Baker,
Horton Lucy E.,
Tirado Mariantonieta,
Reyes Jaimes Oscar,
PerezAlvarez Alexandra,
Zerpa Olga
Publication year - 2013
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2012.05709.x
Subject(s) - cutaneous leishmaniasis , leishmaniasis , medicine , leishmania , subgenus , disease , transmission (telecommunications) , immunology , dermatology , pathology , biology , parasite hosting , genus , botany , world wide web , computer science , electrical engineering , engineering
Leishmaniasis is a diverse group of vector‐borne diseases caused by a subset of predominantly intracellular protozoal species of the genus L eishmania . C utaneous disease may be subdivided into localized, intermediate, and diffuse forms. Intermediate cutaneous leishmaniasis is distributed widely in L atin A merica and is characterized by cutaneous lesions, which may be accompanied by mucosal disease and demonstrate a tendency toward chronicity and relapse as well as resistance to standard treatment regimens. L eishmania parasites of the subgenus V iannia have been identified as the major etiologic agent of this subset of infections. The present review provides a brief perspective on leishmaniasis followed by a review of classification, transmission, clinical presentation, and evolution of disease, immunology, and current treatment approaches for the intermediate/borderline disseminated subset of cutaneous leishmaniasis.