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Disseminated dermatophytic pseudomycetoma caused by Microsporum species
Author(s) -
TiradoGonzález Mariantonieta,
Ball Elizabeth,
Ruiz Angela,
Rodriguez Ysabel,
Goudet Carmen Elena,
Finkel Oksana,
Golan Haim,
de Morentin Helena Martinez,
Sprecher Hanna,
Sprecher Eli,
Gat Andrea
Publication year - 2012
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2012.05550.x
Subject(s) - microsporum gypseum , microsporum canis , terbinafine , microsporum , medicine , dermatophyte , dermatology , trichophyton rubrum , tinea capitis , itraconazole , trichophyton , mycosis , antifungal , surgery
Background Dermatophyte infection is almost exclusively a superficial cutaneous mycosis usually confined to the stratum corneum of nails and hairs of normal hosts. Deep cutaneous and subcutaneous infections due to dermatophytes are exceedingly rare and usually limited to immunosuppressed individuals. These infections remain chronic and persist in spite of treatment. Materials and methods We report two clinical cases of disseminated dermatophytic pseudomycetoma caused by Microsporum gypseum and Microsporum canis in immunosuppressed patients. Results Patient 1, in 2008, showed improvement with fluconazole, cephalothin, and terbinafine treatment for Microsporum gypseum . After suspension of the treatment, new lesions appeared and culture from material was positive. In 2009, she presented confluent papules and nodules forming plaques on her face and neck with the isolation of Microsporum canis . Clinical response to this treatment was poor. Patient 2 was affected by both tinea corporis due to Trichophyton rubrum and dermatophytic pseudomycetoma caused by Microsporum canis . The response to treatment was successful with oral itraconazole and local surgical excision. Conclusions It is important to recognize these atypical presentations of dermatophytic infections in immunosuppressed patients, which may warrant a more aggressive treatment in order to achieve resolution.