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Actinic cheilitis: a treatment review
Author(s) -
Shah Amishi Y.,
Doherty Sean D.,
Rosen Ted
Publication year - 2010
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2010.04580.x
Subject(s) - medicine , dermatology , basal cell , lesion , ablation , trichloroacetic acid , surgery , pathology , biochemistry , chemistry
All other factors being equal, the presence of actinic cheilitis, a pre‐invasive malignant lesion of the lips, doubles the risk of squamous cell carcinoma developing in this anatomic area. Various forms of local ablation,immunomodulation and surgical extirpation have been proposed as therapeutic interventions. This paper critically evaluates the available medical literature to highlight the evidence‐based strength of each recommended therapy for actinic cheilitis. Vermilionectomy remains the gold standard for efficacy; trichloroacetic acid application is easy and convenient, but the least efficacious overall.