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Sweet's syndrome: a retrospective study of 42 admitted patients in a Portuguese hospital
Author(s) -
Borges da Costa João,
Silva Raquel,
Soares de Almeida Luís,
Filipe Paulo,
Marques Gomes Manuel
Publication year - 2009
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2009.04098.x
Subject(s) - medicine , retrospective cohort study , sweet's syndrome , disease , pediatrics , surgery , dermatology
Background Sweet's syndrome is the most common neutrophilic dermatosis, but its pathophysiology is still largely unknown and different subgroups can be defined. Objectives To assess the clinical/laboratory factors in a series of patients with Sweet's syndrome and search for significant differences between defined subgroups. Methods A retrospective study of inpatient files with this diagnosis was made, and patients were included if they fulfilled the classical diagnostic criteria. Data were analyzed with the SPSS package, with a significance level of 5%. Results Forty‐two patients fulfilled the inclusion criteria, with a median age of 50 years. Females comprised 88% of patients, and disease onset occurred in autumn or spring in over 70% of cases. A previous oropharyngeal infection was described by 38% of patients, and a previous or concomitantly diagnosed neoplasm by 10%. In contrast with the literature, the lower extremities were also involved in the majority of patients, and arthralgia was the most frequent extracutaneous manifestation. On bivariate analysis, in patients who reported a previous oropharyngeal infection, the lesions were significantly more frequent in autumn, and a shorter inpatient stay as well as a lower temperature on admission and lower prevalence of arthralgia were observed in the same group. Conclusions The subgroup of patients with a previous oropharyngeal infection had a less severe form of this syndrome.