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Multiple leiomyoma as a possible sign of aggressive renal cancer
Author(s) -
Chia MinWee,
Tay YongKwang,
Tan SuatHoon
Publication year - 2008
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2008.03782.x
Subject(s) - medicine , leiomyoma , abdomen , physical examination , angioleiomyoma , family history , radiology , biopsy , anatomy
A 53‐year‐old Chinese man presented with a history of painful lesions on the chest of 20 years’ duration. He experienced sharp pain especially on touching and after spicy food. The lesions were stable with no increase in size or number. He was otherwise well. There was no significant family history.  Physical examination revealed multiple, grouped, pink papules on the left chest, extending to the right back in a segmental distribution, each measuring 2–5 mm ( Figs 1 and 2). They appeared pearly and keloid‐like, and had a firm consistency. A punch biopsy specimen was obtained and sent for histopathologic examination ( Figs 3 and 4). 1Multiple, grouped, pink papules on the back in a segmental distribution, each measuring 2–5 mm2Multiple, firm, pearly, and keloid‐like leiomyomas on the left chest3Histopathologic examination (hematoxylin and eosin; original magnification, ×10) reveals a circumscribed, nonencapsulated tumor with a Grenz zone below the epidermis4Photomicrograph of biopsy (hematoxylin and eosin, high‐power view) shows interlacing fascicles of bland spindle cells with elongated nuclei and blunt ends, typical of a cutaneous leiomyoma  This revealed a circumscribed, nonencapsulated tumor with a Grenz zone below the epidermis. It was composed of interlacing fascicles of bland spindle cells with elongated nuclei and blunt ends, typical of a cutaneous leiomyoma.  The patient subsequently underwent computed tomography of the abdomen, which did not show any renal or abdominal masses.

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