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Herpes zoster‐associated voiding dysfunction in hematopoietic malignancy patients
Author(s) -
Imafuku Shinichi,
Takahara Masakazu,
Uenotsuchi Takeshi,
Iwato Koji,
Furue Masutaka
Publication year - 2008
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2007.03548.x
Subject(s) - medicine , urinary retention , rash , complication , urinary system , malignancy , disease , dermatology , surgery , gastroenterology
Background Voiding dysfunction is a rare but important complication of lumbo‐sacral herpes zoster. Although the symptoms are transient, the clinical impact on immunocompromised patients cannot be overlooked. Methods To clarify the time course of voiding dysfunction in herpes zoster, 13 herpes zoster patients with voiding dysfunction were retrospectively analyzed. Results Of 13 patients, 12 had background disease, and six of these were hematopoietic malignancies; four of these patients were hematopoietic stem cell transplant (HSCT) recipients. Ten patients had sacral lesions, two had lumbar, and one had thoracic lesions. Interestingly, patients with severe rash, or with hematopoietic malignancy had later onset of urinary retention than did patients with mild skin symptoms (Mann–Whitney U analysis, P = 0.053) or with other background disease ( P = 0.0082). Patients with severe skin rash also had longer durations ( P = 0.035). In one case, acute urinary retention occurred as late as 19 days after the onset of skin rash. Conclusions In immune compromised subjects, attention should be paid to patients with herpes zoster in the lumbo‐sacral area for late onset of acute urinary retention even after the resolution of skin symptoms.