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Nail pigmentation due to hydroxycarbamide
Author(s) -
Ceulen Roeland P. M.,
Frank Jorge,
PobleteGutiérrez Pamela
Publication year - 2007
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2007.03502.x
Subject(s) - hydroxycarbamide , medicine , dermatology , hyperpigmentation , nail (fastener) , nail disease , hypertrichosis , disease , pathology , psoriasis , materials science , metallurgy
A 47‐year‐old male developed both longitudinal melanonychia and periungual hyperpigmentation 6 months after initiation of hydroxycarbamide (synonym: hydroxyurea) therapy for chronic myeloproliferative disease. Based on the clinical symptoms observed in this patient, the broad differential diagnostic spectrum of hyperpigmentation of the nails is briefly reviewed here. In individuals who undergo hydroxycarbamide treatment, melanonychia might sometimes be seen as side effect and always has to be differentiated from subungual malignant melanoma.