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Two therapeutic challenges: periocular and genital vitiligo in children successfully treated with pimecrolimus cream
Author(s) -
Souza Leite Rubens Marcelo,
Craveiro Leite Adriana Aragão
Publication year - 2007
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2007.03282.x
Subject(s) - vitiligo , pimecrolimus , medicine , dermatology , depigmentation , sex organ , pigmentation disorder , tacrolimus , surgery , transplantation , biology , genetics
Vitiligo is characterized by the selective destruction of melanocytes resulting in patches of skin depigmentation. Vitiligo is a therapeutic challenge. Eyebrows, eyelids and genital vitiligo are a therapeutic dilemma, especially in children. The possible side effects of topical corticosteroids and the difficulties for choosing any other adequate treatment option are a major concern. We present two children, one with vitiligo of the eyelids and the other with genital vitiligo, both treated with pimecrolimus 1% cream with almost full repigmentation of the lesions, showing pimecrolimus could be an adequate option for the treatment of vitiligo for these special vitiligo areas in children.