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Nevus lipomatosus cutaneous superficialis with angiokeratoma
Author(s) -
Gao Jian,
Li Chunying,
Liu Ling,
Gao Tianwen
Publication year - 2007
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2007.03184.x
Subject(s) - medicine , angiokeratoma , nodule (geology) , dermatology , papule , dermis , hyperkeratosis , acanthosis , physical examination , papillary dermis , pathology , histopathology , lesion , surgery , paleontology , biology
A 35‐year‐old woman presented with a nodular growth on her right buttock. She had more than a 20‐year history of multiple, asymptomatic, smooth, skin‐colored papules involving her right buttock. The lesions had increased in number over time and had become yellowish or pale red with coalescing nodules exhibiting irregular surfaces. There was no general malaise. Ten years earlier, a diagnosis of connective tissue nevus was made on the basis of a biopsy obtained at a local hospital, but the patient declined treatment at that time. During the past 10 years, the lesions had continued to develop. The medical and social history was otherwise unremarkable, and a general physical examination was negative except for the skin lesions. Cutaneous examination showed soft, yellowish or pale red to violaceous papules and nodules of various sizes with wrinkled surfaces, coalescing into plaques. The lesions were aggregated on her right buttock and extended onto the thigh. The biggest nodule, with a coarse and dry surface, was 40 mm in diameter ( Fig. 1). Histopathologic examination of the largest nodule revealed hyperkeratosis and epidermal hyperplasia with elongated rete ridges. There were thin‐walled, ectatic papillary dermal vessels engorged with red blood cells and masses of mature adipose cells throughout the dermis ( Fig. 2) (Tianwen G, Jianfang S. Non‐epidermal related. In: Tianwen G, Jianfang S, eds. Current Dermatopathology . Beijing: People's Medical Publishing House, 2001: 349–410). A diagnosis of nevus lipomatosus cutaneous superficialis with angiokeratoma was made. The patient declined excision. 1Soft, yellowish or pale red to violaceous coalescing papules and nodules of various sizes, involving the right buttock and extending onto the thigh; the largest nodule has a coarse, dry surface2Histopathology reveals hyperkeratosis, epidermal hyperplasia with elongated rete ridges, and thin‐walled ectatic and engorged vessels in the papillary dermis; there are multiple large aggregates of mature adipose cells throughout the dermis (hematoxylin and eosin, ×20)