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Cutaneous leishmaniasis reactivation 2 years after treatment caused by systemic corticosteroids – first report
Author(s) -
Tuon Felipe Francisco,
Sabbaga Amato Valdir,
FloeterWinter Lucile Maria,
De Andrade Zampieri Ricardo,
Amato Neto Vicente,
Siqueira França Francisco Oscar,
ShikanaiYasuda Maria Aparecida
Publication year - 2007
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2006.03096.x
Subject(s) - medicine , immunosuppression , leishmaniasis , cutaneous leishmaniasis , immunology , leishmania , dermatology , immune system , opportunistic infection , parasite hosting , human immunodeficiency virus (hiv) , viral disease , world wide web , computer science
American tegumentary leishmaniasis (ATL), an endemic anthropozoonosis in various countries in the world, is caused by parasites of the genus Leishmania . Despite reports on ATL reactivation as a result of immunosuppression, to the best of our knowledge, this paper describes the first case of ATL reactivation in its localized form (cutaneous leishmaniasis) associated with the administration of systemic corticosteroids. The possible action of corticosteroids on the host immune response to the parasite in patients with localized cutaneous leishmaniasis is discussed. This report demonstrates the possibility of ATL reactivation in patients using corticosteroids, an observation that should be considered in individuals treated with this medication.