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Epidemiological data and molecular characterization (mtDNA) of Sporothrix schenckii in 13 cases from Mexico
Author(s) -
Arenas Roberto,
Miller Daniel,
CamposMacias Pablo
Publication year - 2007
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2006.03036.x
Subject(s) - sporothrix schenckii , sporotrichosis , mitochondrial dna , molecular epidemiology , epidemiology , sporothrix , medicine , biology , dermatology , genetics , genotype , pathology , gene
Background Sporotrichosis is an endemic mycosis in Mexico and Central America. Objectives To present epidemiological data and characterize molecular subtypes of 13 strains of Sporothrix schenckii , and to correlate clinical and epidemiologic presentation with subtypes. Methodology Thirteen Mexican cases of sporotrichosis were identified, and mitochondrial DNA (mtDNA) from clinical isolates of S. schenckii were analyzed using RFLP Hae III. Molecular types 2, 3, 14, 28, and 29 were observed. Results Clinical presentations and molecular types were consistent with established epidemiologic patterns for S. schenckii in this region. Conclusions This investigation provides further evidence of the strong regional specificity of molecular types of this organism.