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Coexisting pseudoxanthoma elasticum and lupus erythematosus: Report of two cases
Author(s) -
Le Scanff Julie,
Sève Pascal,
Dalle Stephane,
Kodjikian Laurent,
Thomas Luc,
Broussolle Christiane
Publication year - 2007
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2006.03004.x
Subject(s) - pseudoxanthoma elasticum , medicine , dermatology , systemic lupus erythematosus , connective tissue disorder , disease , connective tissue disease , connective tissue , lupus erythematosus , association (psychology) , pathology , autoimmune disease , immunology , philosophy , epistemology , antibody
Pseudoxanthoma elasticum (PXE) is a heritable connective tissue disorder affecting the elastic structures in the body, manifesting with cutaneous, ophthalmologic and cardiovascular findings. The association of PXE and systemic disease is rare, as only six cases have been reported in the literature. We describe herein two cases of coexisting PXE and cutaneous lupus and discuss a possible association. Although a fortuitous association cannot be excluded, the calculated prevalence of the association in our area was much less than in our observation. Given the ocular and vascular complications of PXE, clinicians who treat patients with lupus should be aware of this possible association.