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Nicolau Syndrome: three cases and review
Author(s) -
Luton Kelli,
Garcia Carlos,
Poletti Eduardo,
Koester Glen
Publication year - 2006
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2006.02674.x
Subject(s) - medicine , complication , diclofenac , dermatology , surgery , penicillin , injection site , anesthesia , antibiotics , microbiology and biotechnology , biology
Abstract Nicolau Syndrome, also known as livedo‐like dermatitis (LLD) or embolia cutis medicamentosa (ECM), is an infrequent complication following intramuscular and intra‐articular injection of various drugs. This rare entity is characterized by severe pain and erythematous‐ecchymotic reticular lesions at the injection site, which in many cases lead to necrotic ulcers and scarring. We report three cases of Nicolau Syndrome following injection of diclofenac, penicillin G, and cyanocobalamin.