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Neonatal eosinophilic pustulosis *
Author(s) -
Asgari Maryam,
Leiferman Kristin M.,
Piepkorn Michael,
Kuechle Melanie K.
Publication year - 2006
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2006.02357.x
Subject(s) - medicine , eosinophilia , eosinophilic , spongiosis , pustulosis , dermis , eosinophil , pathology , skin biopsy , dermatology , biopsy , scalp , immunology , osteomyelitis , osteitis , asthma
A pre‐term, 7‐week‐old male infant presented with a recurrent pustular eruption involving his face and scalp with associated peripheral blood eosinophilia. Skin biopsy revealed spongiosis with numerous dermal and epidermal eosinophils without predominant follicular involvement. Immunohistology showed deposition of eosinophil granule major basic protein and eosinophil derived neurotoxin in the dermis and epidermis. He responded to conservative management. We discuss the differential diagnosis of neonatal eosinophilic pustular eruptions and suggest the term ‘neonatal eosinophilic pustulosis’ to best describe our case.