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Secondary extension of Hodgkin's disease to the skin with positive staining for EBV‐encoded latent membrane protein
Author(s) -
RuizGenao D. P.,
DaudénTello E.,
GFVillalta M. J.,
Fraga J.,
GarcíaDíez A.
Publication year - 2005
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2005.02269.x
Subject(s) - medicine , virus , disease , lymph node , epstein–barr virus , immunology , virology , pathology , staining , herpesviridae , viral disease
Cutaneous involvement with Hodgkin's disease in HIV‐positive patients is infrequent. Although the large majority of these cases are pathogenetically linked to Epstein‐Barr virus, demonstration of viral oncogenes in skin involvement of Hodgkin's disease has rarely been performed. We report an HIV‐positive male with aggressive Hodgkin's disease and specific cutaneous involvement. The presence of Epstein‐Barr virus in cutaneous and lymph node samples could be demonstrated by a positive reaction to the Epstein‐Barr virus latent‐encoded membrane protein.