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Mycobacterium marinum with different responses to second‐generation tetracyclines
Author(s) -
Cummins Deborah L.,
Delacerda Davi,
Tausk Francisco A.
Publication year - 2005
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2005.02204.x
Subject(s) - minocycline , mycobacterium marinum , medicine , doxycycline , antimicrobial , antibiotics , microbiology and biotechnology , mycobacterium , pathology , biology , tuberculosis
Background Persistent cutaneous infections with Mycobacterium marinum can follow exposure of injured skin to contaminated water or fish, and can be treated with second‐generation tetracyclines in addition to other antimicrobials. Due to the rarity of this infection, there are few data comparing the different treatment alternatives. Methods We report a patient with culture‐proven M. marinum who was treated with two different second‐generation tetracyclines. Results Our patient failed a 4‐week trial of doxycycline, but responded rapidly to minocycline. Conclusion This case suggests that, despite a similar mechanism, pharmacokinetics, and even sensitivity, these two agents may differ in their effectiveness against strains of M. marinum .