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Hypertrophic and keloidal scars: an approach to polytherapy
Author(s) -
BoutliKasapidou Fotini,
Tsakiri Amalia,
Anagnostou Eleni,
Mourellou Olga
Publication year - 2005
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2004.02570.x
Subject(s) - medicine , cryotherapy , hypertrophic scars , scars , surgery , dermatology , hypertrophic scar , silicone , vulvitis , gynecology , chemistry , organic chemistry , vaginitis
Background Cryotherapy and intralesional corticosteroids have been used separately or in combination as a treatment for hypertrophic and keloidal scars. The addition of silicone gel to the treatment schedule might be of interest. Methods Twenty patients with hypertrophic and keloidal scars received two 15‐s cycles (in total 30 s) of cryotherapy treatments at every session (once monthly for 12 months) with intralesional injections of trimcinolone acetonide 0.1% (10–40 mg/mL, once monthly for 3 months). Topical application of silicone gel was added three times daily (for 12 months). The control group included 10 patients who received treatment with silicone sheeting. Results After 1 year there was improvement in all the parameters studied, especially in terms of symptoms, cosmetic appearance and associated signs ( P < 0.0001) compared to baseline and compared to the control group. Conclusion Our study suggests that polytherapy may be an effective tool in the therapy of hypertrophic and keloidal scars.