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Prodromal bullous pemphigoid
Author(s) -
Lamb Philina M.,
Abell Edward,
Tharp Michael,
Frye Roy,
Deng JauShyong
Publication year - 2006
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2004.02457.x
Subject(s) - medicine , bullous pemphigoid , dermatology , dermatitis herpetiformis , pemphigus vulgaris , presentation (obstetrics) , pemphigus , disease , pemphigoid , retrospective cohort study , surgery , immunology , antibody
Abstract Background Prodromal bullous pemphigoid (PBP) can be difficult to diagnose. Early recognition in its early stages may decrease the morbidity and progression of the disease. Clinical presentations and current treatments available for PBP will be described. Methods A retrospective review was performed on 53 patients diagnosed with PBP. Results Overall, the average disease duration of PBP was 11.8 months. The average age of presentation of PBP was 70.8 years. The most common presentations were urticaria‐like plaques (67.9%), eczema‐like lesions (11.3%), and dermatitis herpetiformis‐like lesions (9.4%). The majority of patients responded well to low doses of systemic corticosteroids, tetracycline, and/or high potency topical corticosteroids. Conclusions Patients with PBP tend to be in their sixth or early seventh decade of life and, on average, the duration of disease is 1 year. The most common presentation of disease is urticaria‐like plaques.