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Is human herpesvirus 7 the causative agent of pityriasis rosea? – a critical review
Author(s) -
Chuh Antonio A. T.,
Chan Henry H. L.,
Zawar Vijay
Publication year - 2004
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2004.02303.x
Subject(s) - pityriasis rosea , medicine , human herpesvirus , human herpesvirus 6 , dermatology , herpesviridae infections , medline , association (psychology) , immunology , herpesviridae , virus , viral disease , biology , biochemistry , philosophy , epistemology
Background Conflicting results on the association of pityriasis rosea and human herpesvirus 7 infection have been reported by different investigators. Aim To review the level of evidence for such an association. Methods Medline was searched with unlimited data entry and 13 reports were retrieved. The data were analyzed for a causative association according to the criteria of Fredericks and Relman, which take into consideration latent infection and the reactivation of viruses characteristic of herpesviruses, and the roles of sequence‐based detection methods. Results None of the criteria was substantiated by the findings of most investigators. Factors leading to the discrepancies of the results were discussed. Conclusion There is currently insufficient evidence that human herpesvirus 7 infection is causally related to pityriasis rosea.