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Evaluation of clinical types of cutaneous lichen planus in anti‐hepatitis C virus seronegative and seropositive Nigerian patients
Author(s) -
Daramola Olaniyi O. M.,
Ogunbiyi Adebola O.,
George Adekunle O.
Publication year - 2003
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2003.01715.x
Subject(s) - nigerians , medicine , oral lichen planus , hepatitis c virus , dermatology , hepatitis c , viral disease , hepatitis , virus , immunology , political science , law
Background The presentation of oral lichen planus in anti‐hepatitis C virus (HCV) seropositive and seronegative patients was previously evaluated, and the keratotic form of oral lichen planus was found to be more prevalent in anti‐HCV seropositive patients. This study evaluated the presentation of cutaneous lichen planus in anti‐HCV seropositive and seronegative Nigerians. Methods Fifty‐seven Nigerians with cutaneous lichen planus were carefully examined to determine the form of lichen planus present. All were screened for the presence of anti‐HCV by second‐generation enzyme‐linked immunosorbent assay (ELISA) and grouped as anti‐HCV seropositive or anti‐HCV seronegative patients. Results Nine patients were anti‐HCV positive. Seven of these seropositive patients had hypertrophic lichen planus. Conclusion Hypertrophic lichen planus in Nigerians is more prevalent with HCV infection.