Premium
DIAGNOSTIC EVALUATION OF THE LUPUS BAND TEST IN DISCOID AND SYSTEMIC LUPUS ERYTHEMATOSUS
Author(s) -
GEORGE RENU,
KURIAN SUSY,
JACOB MARY,
THOMAS KURIAN
Publication year - 1995
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1995.tb01560.x
Subject(s) - medicine , discoid lupus erythematosus , dermatology , systemic lupus erythematosus , lupus erythematosus , systemic disease , connective tissue disease , systemic lupus , immunopathology , immunology , autoimmune disease , pathology , antibody , disease
Background . The usefulness of the lupus band test ( lbt ) in the diagnosis of cutaneous lupus erythematosus remains controversial. The study was done to determine the sensitivity, specificity, and predictive value of the lbt in discoid lupus erythematosus ( dle ) and systemic lupus erythematosus ( sle ). Methods . During the study period, 32 patients with SLE and 28 patients with DLE were included. The final classification of cases was based on the American Rheumatism Association Criteria ( ara ) for sle , histopathology, and consensus of the clinical staff. Thirty controls, 15 each for DLE and sle , were chosen from a group of patients, who had lesions clinically simulating dle and sle , but could be excluded by histopathology, laboratory tests, and follow‐up. Histopathologic examinations and direct immunofluorescence (DIF) tests were done on lesional skin. Results . In dle , the sensitivity of the LE band test was 58% and the specificity 87%. The positive predictive value was 95% and negative predictive value was 32%. In sle the sensitivity was 93% and specificity 87%. The positive predictive value was 64% and negative predictive value 98%. Conclusions . The high negative predictive value of lbt in sle suggests that it is valuable in excluding diseases clinically similar to sle .