Premium
SPECIFIC CUTANEOUS LESIONS IN A CD8+ PERIPHERAL T‐CELL LYMPHOMA
Author(s) -
MARTI ROSA M.,
ESTRACH TERESA,
PALOU JOSÉ,
URBANOISPIZUA ALVARO,
GRATACOS JORDI,
CERVERA RICARDO,
PELIU EVARISTO,
GRAU JOSÉ M.,
MASCARO JOSÉ M.
Publication year - 1992
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1992.tb03979.x
Subject(s) - medicine , lymphoma , pathology , immunophenotyping , peripheral t cell lymphoma , bone marrow , t cell , cd8 , immunohistochemistry , leukemia , antigen , immunology , immune system
Histopathologic, immunohistochemical, and ultrastructural studies were carried out on cutaneous lesions of a 43‐year‐old man with an aggressive peripheral T‐cell lymphoma involving the lung, central nervous system, bone marrow, and skin. Some results are distinctive and not previously reported, such as extremely strong epidermotropism, aberrant CDS+ immunophenotype with lack of one pan T antigen (CDS), and giant cytoplasmic granules. We discuss these features comparing them with other hematologic malignancies usually involving the skin, such as cutaneous T‐cell lymphoma, adult T‐cell leukemia/lymphoma, angiocentric lymphomas, and malignant histiocytosis.