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OCCUPATIONAL OR EXTRINSIC STIMULATION FACTORS AND INITIAL SIGNS OF PROGRESSIVE SYSTEMIC SCLEROSIS
Author(s) -
MAEDA MANABU,
MORI SHUNJI
Publication year - 1992
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1992.tb03566.x
Subject(s) - medicine , progressive systemic sclerosis , stimulation , multiple sclerosis , systemic disease , dermatology , intensive care medicine , physical therapy , immunology , immunopathology , raynaud disease
Forty‐eight patients with progressive systemic sclerosis (PSS) (man‐woman ratio, 7:41) were studied, and detailed questionnaires were used to clarify the relationship between occupational stresses and the initial signs of PSS. All of the patients were right‐handed. Raynaud sign was seen in 37 of the 48 patients (77.1%) as the predominant initial sign of PSS, and it first was noticed on the right index and middle fingers. Three sets of extrinsic aggravating factors, vibration stress, fine hand work with mental stress, and exposure to cold, were believed to be related closely to the development of the initial signs because the initial signs appeared after long‐term exposure to the extrinsic factors.