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PELGEROID‐LIKE ANOMALOUS CELLS IN THE DIAGNOSIS OF NEUTROPHILIC DERMATOSIS ASSOCIATED WITH MYELODYSPLASTIC SYNDROME
Author(s) -
NOGITA TOSHITATSU,
MORIOKA NAOKO,
ISHIBASHI YASUMASA,
KAWASHIMA MAKOTO,
MIZOGUCHI MASAKO,
OTSUKA FUJIO
Publication year - 1992
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1992.tb03544.x
Subject(s) - medicine , abnormality , myelodysplastic syndromes , pathology , myeloproliferative disorders , chromosomal abnormality , bone marrow , karyotype , biology , genetics , gene , psychiatry , chromosome
Neutrophilic dermatoses (ND), with or without accompanying myelodysplastic syndrome (MDS), were examined in terms of nuclear abnormality like pelgeroid anomaly of infiltrating cells into skin lesions. Six IMD accompanying MDS showed 1.0 to 13.5% of such anomalous cells among infiltrating cells. In contrast, ND without accompanying myeloproliferative disorders rarely had such anomalous cells. Our findings suggest that pelgeroid‐like anomalous cells infiltaring into ND are probably a good marker of underlying MDS.