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HORMONAL STATUS IN POSTMENOPAUSAL ANDROGENETIC ALOPECIA
Author(s) -
GEORGALA S.,
GOURGIOTOU K.,
KASSOULI S.,
STRATIGOS J.D.
Publication year - 1992
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1992.tb03542.x
Subject(s) - menopause , medicine , endocrinology , sex hormone binding globulin , hormone , testosterone (patch) , androgen , hair follicle , postmenopausal women , androgen receptor , physiology , prostate cancer , cancer
The development of androgenetic alopecia is thought to be caused by increased androgen action on hair follicles with menopause. Testosterone, estradiol and sex hormone binding globulin (SHBG) serum levels were determined in ten postmenopausal women with androgenetic alopecia and in ten sex and age matched healthy controls. No statistically significant differences were found in the hormone levels between the patients and the controls. These findings suggest that a genetically determined functional alteration of androgen receptors and/or a metabolic disturbance may exist in the hair follicle keratinocytes in androgenetic alopecia.