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ERYTHROMYCIN VERSUS CEEADROXIL IN THE TREATMENT OF SKIN INFECTIONS
Author(s) -
HESKEL NEIL S.,
SIEPMAN NANCY C.,
PICHOTTA PHILIP J.,
GREEN ELIZABETH M.,
STOLL RALPH W.
Publication year - 1992
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1992.tb03255.x
Subject(s) - cefadroxil , erythromycin , medicine , adverse effect , skin infection , dermatology , antibiotics , pharmacology , cephalosporin , microbiology and biotechnology , bacteria , staphylococcus aureus , genetics , biology
Erythromycin is often overlooked for the treatment of skin and skin structure infections. We evaluated the efficacy and safety of erythromycin particles in tablets and of cefadroxil in 164 patients with skin infections; both treatments were given as 500 mg twice daily. One hundred percent of erythromycin and 96% of cefadroxil patients were clinically cured or improved, and 98% of susceptible pathogens were eradicated in both groups. Only three erythromycin patients and one cefadroxil patient left the study early because of GI‐related adverse events. Erythromycin, therefore, was as effective and safe as cefadroxil in the treatment of mild‐to‐moderate skin infections.