Premium
IMMUNOHISTOCHEMICAL IDENTIFICATION OF PENICILLIUM MARNEFFEI BY MONOCLONAL ANTIBODY
Author(s) -
ARRESE ESTRADA JORGE,
STYNEN DIRK,
CUTSEM JAN,
PIÉRARDFRANCHIMONT CLAUDINE,
PIÉRARD GERALD E.
Publication year - 1992
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1992.tb02670.x
Subject(s) - penicillium marneffei , medicine , immunohistochemistry , monoclonal antibody , penicillium , identification (biology) , antibody , microbiology and biotechnology , pathology , virology , immunology , biology , human immunodeficiency virus (hiv) , coinfection , genetics , botany
We present an experimental study on the immunohistochemical identification of Penicillium marneffei in paraffin‐embedded, formalin‐fixed tissue. The monoclonal antibody EB‐A1 detects a specific galactomannan that appears to have at least one epitope identical in P. marneffei and Aspergillus sp. This immunohistochemical approach could be useful in the diagnosis of a rare disease, penicilliosis marneffei, which proves to be difficult to identify by conventional microscopy.