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Characterization of Circulating Lymphocytes by Monoclonal Antibodies in Childhood and Adult Leprosy
Author(s) -
Sehgal Virendra N.,
Chaudhry Anoop,
Sharma Vinay K.,
Gupta Chander K.
Publication year - 1991
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1991.tb04786.x
Subject(s) - medicine , leprosy , monoclonal antibody , incidence (geometry) , immunology , antibody , disease , lymphocyte , peripheral blood , monoclonal , lymphocyte subsets , pathology , immune system , t cell , physics , optics
Peripheral blood lymphocyte assays using monoclonal antibodies were done in 66 patients with leprosy, consisting of 25 children and 41 adults. The results were statistically analyzed for correlations, if any, among the different age groups and matched controls. The results, however, failed to show any significant correlation, nor was it possible to draw any conclusion as to why the disease spectrum in children tends to be incomplete (ie, there is a low incidence of the highly bacilliferous form of disease expression).