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Disseminated Histoplasmosis Presenting as an Ulcerated Verrucous Plaque in a Human Immunodeficiency Virus‐Infected Man
Author(s) -
Cohen Philip R.,
Held Jonathan L.,
Grossman Marc E.,
Ross Mitchell J.,
Silvers David N.
Publication year - 1991
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1991.tb04220.x
Subject(s) - histoplasmosis , medicine , ketoconazole , dermatology , mycosis , human immunodeficiency virus (hiv) , immunopathology , viral disease , sida , pathology , immunology , dimorphic fungus , transmission (telecommunications) , antifungal , biology , electrical engineering , engineering , genetics , yeast
A 46‐year‐Old homosexual man with disseminated histoplasmosis and human immunodeficiency virus (HIV) infection had a histoplasmosis‐related ulcerated verrucous plaque above his left upper lip; systemic and cutaneous disease manifestations of histoplasmosis resolved with daily ketoconazole therapy. Disseminated histoplasmosis, with similar cutaneous features, also was present in his HIV‐seropositive male sexual partner. The possibility of human‐to‐human transmission of histoplasmosis between these patients is considered and the skin lesions of systemic fungal infections in HIV‐infected patients are reviewed.