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Sweet Syndrome Associated with Acute Myelogenous Leukemia
Author(s) -
Dompmartin Anne,
Troussard Xavier,
Lorier Elisabeth,
Jacobs F.,
Reman O.,
Leroy D.,
Leporrier M.
Publication year - 1991
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1991.tb03491.x
Subject(s) - sweet's syndrome , medicine , acute myelomonocytic leukemia , sweet syndrome , pathophysiology , leukemia , immunology , acute leukemia , pathology
A case of Sweet syndrome in a patient with an acute myelomonocytic leukemia is reported, it is an unusual case simulating a facial erysipela. This case illustrates the difficulty in differentiating infection from Sweet syndrome in an immuno‐compromised patient. The negative cultures, ineffective antibiotics, and histopathologic examination results allowed the onset of corticosteroid therapy. The phagocytic function of the neutrophils studied by chemoluminescence was normal in the patient. The physiopathology of Sweet syndrome is discussed, in particular the role of cytokines in the accumulation of granulocytes.