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Pemphigus Therapy with Oral Prednisolone Regimens A 5‐Year Study
Author(s) -
Ratnam K. V.,
Phay K. L.,
Tan C. K.
Publication year - 1990
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1990.tb04765.x
Subject(s) - medicine , regimen , prednisolone , pemphigus , incidence (geometry) , surgery , gastroenterology , dermatology , physics , optics
Twenty‐two newly diagnosed patients with pemphigus were randomly divided into two groups of 11 each. One group was placed on a high‐dose prednisolone (120 mg/day) therapy and the other group on a low‐dose (60 mg/day) therapy. The patients were followed for 5 years. Although a rapid initial control of the pemphigus appeared to be achieved with the high‐dose regimen, this regimen did not have any long‐term benefit over the low‐dose regimen with respect to the frequency of relapse or in the incidence of complications.