Premium
Self‐Limiting Acrodermatitis Enteropathica
Author(s) -
Sharma N. L.,
Sharma R. C.,
Gupta K. R.,
Sharma R. P.
Publication year - 1988
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1988.tb00926.x
Subject(s) - acrodermatitis enteropathica , medicine , acrodermatitis , limiting , weaning , zinc deficiency (plant disorder) , zinc , dermatology , endocrinology , pathology , micronutrient , mechanical engineering , materials science , alternative medicine , engineering , metallurgy
A variant of acrodermatitis enteropathica is described that has its onset before weaning and clears when the child starts its normal solid diet. A pedigree with three interrelated families is reported where 10 children were afflicted with this variant. They had symptoms of hypozincemia for a brief period during infancy. At the time of this study, they were symptom‐free and their serum zinc levels were found to be within normal limits. The term “self‐limiting acrodermatitis enteropathica” is proposed for the variant. In one lactating mother, the mammary zinc secretion was determined and was found to be deficient and unresponsive to oral zinc supplements. The possible mode of inheritance is also discussed.