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A Speculative on Psoriasis as an Evolutionary Consequence
Author(s) -
Stone Orville J.
Publication year - 1987
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1987.tb02307.x
Subject(s) - psoriasis , medicine , trait , speculation , inflammation , dermatology , immunology , computer science , economics , macroeconomics , programming language
Summary I speculate that if the inflammatory reactivity of all humans were quantitated, the results would fall on a bell‐shaped curve. Psoriasis or the psoriatic trait is the most reactive 3%. Any attempt by evolution to shift the general inflammatory response to lesser activity would result in consequences more significant than psoriasis. This speculation predicts that we might have to settle for quantitative rather than qualitative changes in inflammation in psoriasis.