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Linear IgA Bullous Dermatosis Mimicking Erythema Multiforme in Adult
Author(s) -
Argenyi Zsolt B.,
Bekcfeld Wuma F.,
Valenzuela Rafael,
Mcmahon James T.,
Tomecki Kenncth J.
Publication year - 1987
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1987.tb02292.x
Subject(s) - erythema multiforme , medicine , dermatitis herpetiformis , immunoelectron microscopy , pathology , bullous pemphigoid , dermatology , lamina densa , immunohistochemistry , antibody , immunology , ultrastructure , disease
This report describes a 49‐year‐old woman with an erythema multiforme‐like rash and direct immunofluorescence showing linear IgA deposits at the dernmepidermal junction. Light microscopy revealed features of bullous pemphigoid, dermatitis herpetiformis, and erythema multiforme: immunoelectron microscopy demonstrated IgA deposition beneath the lamina densa about anchoring fibrils. These data provide additional information about the variable clinical and histologic manifestations of the adult linear IgA bullous dermatosis and emphasize the diagnostic dilemmas of light microscopy, which are resolved by immunohistochemical methods.