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Outpatient Therapy of Bite Wounds
Author(s) -
Goldstein Ellie J. C.,
Reinhardt John F.,
Murray Patricia M.,
Finecold Sydney M.
Publication year - 1987
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1987.tb00544.x
Subject(s) - medicine , penicillin , amoxicillin , clavulanic acid , dicloxacillin , anaerobic bacteria , surgery , diarrhea , antimicrobial , antibiotics , microbiology and biotechnology , bacteria , genetics , biology
Thirty patients received penicillin (17 of these also received dicloxacillin) and 31 received amoxicillin/clavulanic add in a randomized study of the outpatient management of bite wounds. A wide variety of aerobic (185 strains) and anaerobic (47 strains) bacteria were isolated from these wounds. The control and study regimens were equally effective. There were four therapeutic failures in all. Aggressive wound management along with antimicrobial therapy led to a 87–96% cure rate. Loose stools or diarrhea was a more frequent side effect with amoxicillin/clavulanic acid than with penicillin ± dicloxacillin.