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Dapsone‐induced Peripheral Neuropathy
Author(s) -
Ahrens Edwin M.,
Meckler Roy J.,
Callen Jeffrey P.
Publication year - 1986
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1986.tb02253.x
Subject(s) - medicine , dapsone , peripheral neuropathy , sulfapyridine , leprosy , dermatitis herpetiformis , dermatology , peripheral , surgery , disease , chemistry , organic chemistry , diabetes mellitus , endocrinology
A young man with dermatitis herpetiformis developed fatigue and neurologic complaints 4 years after he began oral dapsone therapy. Neurologic examination and nerve conduction studies confirmed the presence of a combined motor and sensory peripheral neuropathy. The symptomatic improvement reported by the patient was supported by improvement in the nerve conduction studies after cessation of dapsone therapy. Substitution of sulfapyridine did not adversely affect the resolution of his neuropathy.