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Topical Zinc Therapy for Acne Vulgaris
Author(s) -
Cochran Ronald J.,
Tucker Stephen B.,
Flannigan Stephen A.
Publication year - 1985
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1985.tb05425.x
Subject(s) - acne , medicine , placebo , zinc , dermatology , significant difference , placebo group , double blind study , double blind , pathology , alternative medicine , materials science , metallurgy
Abstract: A double‐blind study of 30 patients with mild to moderate acne vulgaris was conducted to evaluate the efficacy of a topically applied 2% zinc sulfate solution for acne therapy. Over a 12‐week period, no difference was noted between placebo‐ and zinc‐treated participants in regard to either the number or type of acne lesions. The irritancy due to topically applied zinc was significantly greater (p 0.05) than that due to the placebo. Zinc serum levels were not significantly elevated between the two regimens before, during, or after treatment. This study suggests that topical zinc therapy alone is not of significant benefit in the treatment of acne vulgaris.