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Combination Therapy of Sodium Stibogluconat and Rifampin in Cutaneous Leishmaniasis
Author(s) -
Pareek S.S.
Publication year - 1984
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1984.tb05669.x
Subject(s) - sodium stibogluconate , medicine , cutaneous leishmaniasis , leishmaniasis , rifampicin , dermatology , surgery , immunology , tuberculosis , pathology
Thirty‐two patients having cutaneous leishmaniasis were divided into two groups: 16 were treated with sodium stibogluconate 600 mg intramuscularly daily for 12 days and 16 were treated with 600 mg rifampin daily for 21 days. The failure rate was 56% and 50%, respectively. The 17 patients who did not respond were treated with a combination of two drugs, which produced bettter results in 13 of the 17 patients.