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T‐Lymphocyte Subsets in Leprosy
Author(s) -
GonzalezAmaro Roberto,
Moncada Benjamin,
Loredeo Carmen E.,
Lourdes Baranda Maria
Publication year - 1983
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1983.tb02143.x
Subject(s) - leprosy , lepromatous leprosy , medicine , immunology , monoclonal antibody , lymphocyte subsets , suppressor , immunofluorescence , t lymphocyte , indirect immunofluorescence , antibody , antigen , t cell , immune system , cancer
Immunologic abnormalities in T cells have been reported in patients with lepromatous leprosy. Ten patients with leprosy (eight lepromatous, one dimorphous, one tuber‐culoid) were studied in order to detect the proportions of total T lymphocytes and helper as well as suppressor subsets, using monoclonal antibodies in an indirect immunofluorescence test. Percentages of total T cells, suppressor cells, as well as helper subsets were similar in leprosy patients as compared with age‐matched controls. This study could be considered a preliminary one to be followed by functional assays.