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A ZINC‐DEFICIENCY DERMATITIS IN PATIENTS ON TOTAL PARENTERAL NUTRITION
Author(s) -
STROBEL CORY T.,
BYRNE WILLIAM J.,
ABRAMOVITS WILLIAM,
NEWCOMER VICTOR J.,
BLEICH RICHARD,
AMENT MARVIN E.
Publication year - 1978
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1978.tb06003.x
Subject(s) - medicine , parenteral nutrition , acrodermatitis enteropathica , zinc , atopic dermatitis , etiology , acrodermatitis , zinc deficiency (plant disorder) , dermatology , complication , casein , gastroenterology , micronutrient , food science , pathology , chemistry , materials science , alternative medicine , metallurgy
Three patients on home total parenteral nutrition utilizing a synthetic amino acid solution developed a dermatitis consistent with acrodermatitis enteropathica after 30, 43 and 62 days of therapy. The dermatitis resolved after changing to casein hydrolysate in 2 patients and after full oral alimentation in the third. Although measured serum zinc levels were repeatedly normal to elevated in all patients, sufficient retrospective data analysis combined with literature review on this subject, clearly implicates zinc deficiency as the etiology for their dermatitis. Adequate zinc supplementation of synthetic amino acid solutions is essential in order to avoid this complication.