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MUSCLE INVOLVEMENT IN LEPROSY AND ITS CORRELATION WITH SERUM ALDOLASE ACTIVITY
Author(s) -
SHIEMY SALEH,
HEFNAWY HASSAN,
FATTAH ALY ABDEL,
HAWARY MOHAMMED F.,
FARES RIFKY
Publication year - 1977
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4362.1977.tb00787.x
Subject(s) - aldolase a , leprosy , medicine , lepromatous leprosy , biopsy , bacilli , muscle biopsy , pathology , fructose bisphosphate aldolase , enzyme , biochemistry , biology , bacteria , genetics
Thirty‐six leprosy patients underwent muscle biopsy; the specimens were studied for serum aldolase activity. The authors concluded that muscle degeneration occurs only in lepromatous leprosy due to direct invasion by leprosy bacilli increasing serum aldolase activity during the active degenerative phase of the muscle fibers.